API Obeticholic acid CAS 459789-99-2 maka foto biliary cholangitis

API Obeticolic acid CAS 459789-99-2 maka cholangitis biliary

Nkọwa dị mkpirikpi:

A na-eji Obeticholic acid naanị ya ma ọ bụ na ngwakọta ọgwụgwọ maka ụfọdụ ọrịa imeju (primary biliary cholangitis-PBC).

Kpọtụrụ: Erica Zheng

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Nkọwa ngwaahịa

Mkpado ngwaahịa

Nkọwa

A na-eji Obeticholic acid naanị ya ma ọ bụ na ngwakọta ọgwụgwọ maka ụfọdụ ọrịa imeju (primary biliary cholangitis-PBC).

Nkọwapụta:

Aha ngwaahịa	Obeticholic acid
Aha Chemical	6-Ethylchenodeoxycholic acid
Aha ọzọ	3A, 7A -DIHYDROXY-6A -ETHYL-5B-CHOLAN-24-OIC ACID;Obeticholic acid 6-ECDCA;6alpha-Ethyl-chenodeoxycholic acid;6-Ecdca;6-Ethylchenodeoxycholic acid;6alph;Obeticholic747 -ECDCA)
Nọmba CAS	459789-99-2
Usoro ihe omimi	C26H44O4
Ibu Formula	420.63
Ọdịdị	Ọcha ntụ ntụ
Nyocha	99.0% nkeji
Njupụta	1.091 g/cm3
Ebe Na-agbaze	108-110 Celsius C
Ebe esi nri	562.9±25.0C
ngwugwu	20kg / akpa / drum, 25kg / akpa / drum, ma ọ bụ dị ka ị chọrọ
Nchekwa	Chekwaa akpa ahụ mechiri emechi na ebe kpọrọ nkụ na ebe dị jụụ.Ekpughela ìhè anyanwụ kpọmkwem.
COA & MSDS	Dị

Ojiji

Obeticholic acid bụ dihydroxy-5beta-cholanic acid nke bụ chenodeoxycholic acid na-ebu ihe mgbakwunye ethyl ọzọ na ọnọdụ 6alpha.Bile acid nke ọkara synthetic nke na-arụ ọrụ dị ka agonist X na-anabata Farnesoid ma na-eji ya maka ọgwụgwọ nke biliary cholangitis mbụ.Ọ nwere ọrụ dị ka farnesoid X agonist receptor na onye na-ahụ maka hepatoprotective.Ọ bụ dihydroxy-5beta-cholanic acid, 3alpha-hydroxy steroid na 7alpha-hydroxy steroid.Ọ na-enweta site na chenodeoxycholic acid.
Obeticholic acid (OCA) bụ bile acid nke synthetically gbanwetụrụ na agonist nwere ike nke farnesoid X nuclear receptor (FXR) nke a na-eji agwọ ọrịa imeju gụnyere isi biliary cholangitis.