API Donepezil HCl CAS 120011-70-3 Maka Ọrịa Alzheimer

Nkọwa dị mkpirikpi:

Donepezil Hydrochloride bụ nnu hydrochloride nke ihe nrụpụta piperidine nwere ọrụ na-akwalite neurocognitive.Donepezil reversibly na-egbochi acetylcholinesterase, si otú na-egbochi hydrolysis nke neurotransmitter acetylcholine na, n'ihi ya, na-amụba ọrụ ya.

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Nkọwa ngwaahịa

Mkpado ngwaahịa

Nkọwa

A na-eji Donepezil agwọ mgbagwoju anya metụtara ọrịa Alzheimer.

Nkọwapụta:

Aha ngwaahịa	Donepezil Hydrochloride
Aha Chemical	1h-inden-1-otu,2,3-dihydro-5,6-dimethoxy-2- ((1- (phenylmethyl)-4-piperidinyl) m
Aha ọzọ	Donepezil hcl; Donezepilhydrochloride; DonepezilHydrochloride (200mg); 2-( (1-Benzylpiperidin-4-yl) Methyl) -5,6-diMethoxy-2,3-dihydro-1H-inden-1-onehydrochloride;2,3-Dihydro -5,6-diMetChemicalbookhoxy-2-[[1- (phenylMethyl)-4-piperidinyl] Methyl] -; 2- (1-Benzyl-4-piperidylmethyl) -5,6-dimethoxy-1-indanoneHydrochloride; Donepezil (Aricept) );DonepezilHydrochlorideForMⅠ
Nọmba CAS	120011-70-3
Usoro ihe omimi	C24H30ClNO3
Ibu Formula	415.95
Ọdịdị	kristal siri ike na-acha ọcha ruo na-acha ọcha
Nyocha	98.0% nkeji
Ebe Na-agbaze	220-222 Celsius C
Ebe esi nri	527.9 C na 760 mmHg
ngwugwu	20kg / akpa / drum, 25kg / akpa / drum, ma ọ bụ dị ka ị chọrọ
Nchekwa	Chekwaa akpa ahụ mechiri emechi na ebe kpọrọ nkụ na ebe dị jụụ.Ekpughela ìhè anyanwụ kpọmkwem.
COA & MSDS	Dị
Ngwa	Maka ebumnuche nyocha

Asambodo nyocha/COA:

Nnwale ihe	Nkọwapụta	Nsonaazụ
Ọdịdị	Gbanyụọ ọcha na ntụ ntụ kristal ọcha	Na-akwado
Solubility	Soluble soluble na chloroform, soluble n'ime mmiri na Acetic acid, soluble dị ntakịrị na Acetonitrile na ethanol, nke na-adịghị edozi na Ethylacetoacetate na n-hexane.	Na-akwado
njirimara	(1) Site IR absorption, Iji dakọtara na-arụ ọrụ ọkọlọtọ.	Na-akwado
	(2) Oge njide nke isi ọnụ ọgụgụ kachasị elu nke ihe nlele kwesịrị ikwekọ na nke ọkọlọtọ ọrụ.	Na-akwado
	(3) Nnwale maka chlorides.Na-atụgharị na ule maka Chlorides.	Na-akwado
Mmiri	≤0.4%	0.31%
Ihe fọdụrụ na mgbanye	≤0.1%	0.02%
Ihe metụtara ya	Desbenzyl merepezl^a≤0.15% Analogue nke Donepezil pyridine^b≤0.15% Donepezilzilbenzyl bromide^c≤0.15% Dehydrodeoxy merepezil^d≤0.15% Deoxy merepezil^e≤0.15% Otu adịghị ọcha ọ bụla ≤0.10% Ngụkọta ≤0.5%	Achọpụtaghị Achọpụtaghị 0.02% Achọpụtaghị Achọpụtaghị 0.05% 0.18%
Igwe dị arọ	≤20ppm	≤20ppm
Ihe mgbaze fọdụrụnụ	Methanol ≤0.3%Ethanol ≤0.5%Ethyl acetate ≤0.5% Toluene≤0.089% Acetic acid ≤0.5%	Achọpụtaghị Achọpụtaghị Achọpụtaghị Achọpụtaghị Achọpụtaghị
Nyocha	N'elu ala a mịrị amị, C₂₄H₂₉NO₃HCl kwesịrị ịbụ 98.0% ruo 102.0%.	99.52%