API Chlormadinone Acetate CMA 302-22-7 Estrogen Hormones Ụmụ nwanyị

Nkọwa dị mkpirikpi:

Chlormadinone acetate bụ progestin na ọgwụ antiandrogen nke a na-eji na ọgwụ mgbochi ịmụ nwa iji gbochie afọ ime, dịka akụkụ nke ọgwụgwọ hormone menopausal, na ọgwụgwọ ọrịa gynecological, na ọgwụgwọ nke ọnọdụ androgen-based dị ka ụba prostate na prostate cancer. ụmụ nwoke na ihe otutu na hirsutism na ụmụ nwanyị.

 

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Nkọwa ngwaahịa

Mkpado ngwaahịa

Nkọwa

Chlormadinone acetate (CMA) bụ ike progesterone receptor (PR) agonist, akụkụ androgen receptor (AR) antagonist na onye na-adịghị ike glucocorticoid receptor (GR) antagonist.Chlormadinone na-ejikọta na PR, nke na-eme ka nkwupụta nke progesterone na-anabata mkpụrụ ndụ ihe nketa.

Nkọwapụta:

Aha ngwaahịa Chlormadinone acetate
Aha Chemical 17α-acetoxy-6-chloro-4,6-pregnadiene-3,20-dione
Aha ọzọ Clormadinoneacetate, chloromadinone17-acetate; 6-Chloro-17-acetoxy-4,6-pregnadiene-3,20-dione; 17α-Acetoxy-6-chloro-4,6-pregnadiene-3,20-dione,6-Chloro- 6-dehydro-17a-acetoxyprogesterone, Gestafortin, Matrol, Menstridyl,6-Chloro-17α-hydroxy-4,6-pregnadiene-3,20-dione17-acetate;17-alpha-acetoxy-;ChChemicalbooklormadinoneacetate,αtoxy-17 -chloro-4,6-pregnadiene-3,20-dione,6-Chloro-17α-hydroxy-4,6-pregnadiene-3,20-dione17-acetate,6-Chloro-6-dehydro-17α-acetoxyprogesterone,Gestafortin , Matrol, Ndị ikom; (8R,9S,10R,13S,14S,17R) -17-acetyl-6-chloro-10,13-diMethyl-3-oxo-2,3,8,9,10,11,12 ,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-ylacetate
Nọmba CAS 302-22-7
Usoro ihe omimi C23H29ClO4
Ibu Formula 404.93
Ọdịdị Ọcha Ka-acha odo odo kristal ntụ ntụ;Enweghị isi, enweghị ụtọ
Nyocha 98.0% nkeji
Ebe Na-agbaze 212°C
Ebe esi nri 512.5±50.0 Celsius
Ọnụ kacha elu absorption 1.1345 g/cm3
ngwugwu 20kg / akpa / drum, 25kg / akpa / drum, ma ọ bụ dị ka ị chọrọ
Nchekwa Chekwaa akpa ahụ mechiri emechi na ebe kpọrọ nkụ na ebe dị jụụ.Ekpughela ìhè anyanwụ kpọmkwem.
COA & MSDS Dị
Ngwa Maka ebumnuche nyocha

Asambodo nyocha/COA:

Nnwale OKWU anabatara Nsonaazụ
njirimara TLC Nke dị mma
  UV ụdịdị Nke dị mma
  Ụdị ụdịdị dị iche iche Nke dị mma
Njirimara kristal ntụ ntụ ọcha ma ọ bụ odo odo kwekọrịtara
Ebe mgbaze 211 ~ 215 ℃ 211-214 ℃
Ntụgharị anya pụrụ iche ﹣10° ~﹣14° ﹣12.5°
Solubility soluble n'efu na chloroform, soluble na acetonitrile, soluble ntakịrị na ethanol na ether na nke a na-adịghị ahụkebe na mmiri. kwekọrịtara
Ọnwụ na ihicha ≤0.5% 0.21%
Ihe fọdụrụ na mgbanye ≤0.1% 0.04%
Steroid ndị ọzọ ≤1.0% 0.59%
Ọla dị arọ ≤20ppm Gafe
Arsenic ≤2pm Gafe
Nyocha ≥98.0% 98.9%
Ihe mgbaze ndị fọdụrụ (GC) Acetone ≤5000ppm
Methanol≤3000ppm
Pyridine≤200ppm
Gafe
Gafe
Gafe

Ojiji

Chlormadinone acetate bụ progestin na ọgwụ antiandrogen nke a na-eji na ọgwụ mgbochi ịmụ nwa iji gbochie afọ ime, dịka akụkụ nke ọgwụgwọ hormone menopausal, na ọgwụgwọ ọrịa gynecological, na ọgwụgwọ nke ọnọdụ androgen-based dị ka ụba prostate na prostate cancer. ụmụ nwoke na ihe otutu na hirsutism na ụmụ nwanyị.

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Etiti oge

≤100kg: n'ime atọ ọrụ ụbọchị mgbe ugwo natara.

100kg: otu izu

Ihe atụ

Dị.

ngwugwu

20kg / akpa / drum, 25kg / akpa / drum

ma ọ bụ dị ka ịchọrọ.

Nchekwa

Chekwaa akpa ahụ mechiri emechi na ebe kpọrọ nkụ na ebe dị jụụ.

Ekpughela ìhè anyanwụ kpọmkwem.

Asambodo

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Ihe anyị nwere ike inye

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