Chlormadinone acetate (CMA) bụ ike progesterone receptor (PR) agonist, akụkụ androgen receptor (AR) antagonist na onye na-adịghị ike glucocorticoid receptor (GR) antagonist.Chlormadinone na-ejikọta na PR, nke na-eme ka nkwupụta nke progesterone na-anabata mkpụrụ ndụ ihe nketa.
Aha ngwaahịa | Chlormadinone acetate |
Aha Chemical | 17α-acetoxy-6-chloro-4,6-pregnadiene-3,20-dione |
Aha ọzọ | Clormadinoneacetate, chloromadinone17-acetate; 6-Chloro-17-acetoxy-4,6-pregnadiene-3,20-dione; 17α-Acetoxy-6-chloro-4,6-pregnadiene-3,20-dione,6-Chloro- 6-dehydro-17a-acetoxyprogesterone, Gestafortin, Matrol, Menstridyl,6-Chloro-17α-hydroxy-4,6-pregnadiene-3,20-dione17-acetate;17-alpha-acetoxy-;ChChemicalbooklormadinoneacetate,αtoxy-17 -chloro-4,6-pregnadiene-3,20-dione,6-Chloro-17α-hydroxy-4,6-pregnadiene-3,20-dione17-acetate,6-Chloro-6-dehydro-17α-acetoxyprogesterone,Gestafortin , Matrol, Ndị ikom; (8R,9S,10R,13S,14S,17R) -17-acetyl-6-chloro-10,13-diMethyl-3-oxo-2,3,8,9,10,11,12 ,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-ylacetate |
Nọmba CAS | 302-22-7 |
Usoro ihe omimi | C23H29ClO4 |
Ibu Formula | 404.93 |
Ọdịdị | Ọcha Ka-acha odo odo kristal ntụ ntụ;Enweghị isi, enweghị ụtọ |
Nyocha | 98.0% nkeji |
Ebe Na-agbaze | 212°C |
Ebe esi nri | 512.5±50.0 Celsius |
Ọnụ kacha elu absorption | 1.1345 g/cm3 |
ngwugwu | 20kg / akpa / drum, 25kg / akpa / drum, ma ọ bụ dị ka ị chọrọ |
Nchekwa | Chekwaa akpa ahụ mechiri emechi na ebe kpọrọ nkụ na ebe dị jụụ.Ekpughela ìhè anyanwụ kpọmkwem. |
COA & MSDS | Dị |
Ngwa | Maka ebumnuche nyocha |
Nnwale | OKWU anabatara | Nsonaazụ |
njirimara | TLC | Nke dị mma |
UV ụdịdị | Nke dị mma | |
Ụdị ụdịdị dị iche iche | Nke dị mma | |
Njirimara | kristal ntụ ntụ ọcha ma ọ bụ odo odo | kwekọrịtara |
Ebe mgbaze | 211 ~ 215 ℃ | 211-214 ℃ |
Ntụgharị anya pụrụ iche | ﹣10° ~﹣14° | ﹣12.5° |
Solubility | soluble n'efu na chloroform, soluble na acetonitrile, soluble ntakịrị na ethanol na ether na nke a na-adịghị ahụkebe na mmiri. | kwekọrịtara |
Ọnwụ na ihicha | ≤0.5% | 0.21% |
Ihe fọdụrụ na mgbanye | ≤0.1% | 0.04% |
Steroid ndị ọzọ | ≤1.0% | 0.59% |
Ọla dị arọ | ≤20ppm | Gafe |
Arsenic | ≤2pm | Gafe |
Nyocha | ≥98.0% | 98.9% |
Ihe mgbaze ndị fọdụrụ (GC) | Acetone ≤5000ppm Methanol≤3000ppm Pyridine≤200ppm | Gafe Gafe Gafe |
Chlormadinone acetate bụ progestin na ọgwụ antiandrogen nke a na-eji na ọgwụ mgbochi ịmụ nwa iji gbochie afọ ime, dịka akụkụ nke ọgwụgwọ hormone menopausal, na ọgwụgwọ ọrịa gynecological, na ọgwụgwọ nke ọnọdụ androgen-based dị ka ụba prostate na prostate cancer. ụmụ nwoke na ihe otutu na hirsutism na ụmụ nwanyị.
Kedu ka m ga-esi were Chlormadinone acetate?
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Etiti oge
≤100kg: n'ime atọ ọrụ ụbọchị mgbe ugwo natara.
>100kg: otu izu
Ihe atụ
Dị.
ngwugwu
20kg / akpa / drum, 25kg / akpa / drum
ma ọ bụ dị ka ịchọrọ.
Nchekwa
Chekwaa akpa ahụ mechiri emechi na ebe kpọrọ nkụ na ebe dị jụụ.
Ekpughela ìhè anyanwụ kpọmkwem.